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"Cognitive closure refers to the possibility that certain problems cannot be explained by the human mind. In philosophy of science some have adopted the position that some problems are forever outstanding, and not because their solutions do not exist, but rather because the solutions cannot be properly conceived. This philosophical position is also sometimes called transcendental naturalism, anti-constructive naturalism, or new mysterianism. It proposes that the human mind is unavoidably biased, or “closed” in some areas of thinking, and so these areas then are forever mysteries. The most prominent defender of the cognitive closure thesis is philosopher Colin McGinn.[1]"

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Cognitive closure (philosophy) - Wikipedia, the free encyclopedia

Kant and Noumena

As argued in Kant’s Critique of Pure Reason, human thinking is unavoidably structured by Categories of the understanding:

Quantity – Unity, Plurality, Totality.
Quality – Reality, Negation, Limitation.
Relation – Inherence and Subsistence, Causality and Dependence, Community.
Modality – Possibility or Impossibility, Existence or Non-Existence, Necessity or Contingence.

These are ideas to which there is no escape, thus they pose a limit to thinking. What can be known through the categories is called phenomena and what is outside the categories is called noumena and is unthinkable, separate from the mind. Unfortunately for metaphysicians, this includes “things in themselves”.

Wittgenstein and limits of language

Much like Kant, Ludwig Wittgenstein identifies a similar limit, though he articulates it not as a limit to thought, but as a limit to language. This is because a sentence makes sense just insofar as it refers to something meaningful. The limits of what exists in reality then are the same as the limits of sentences:

“in order to be able to draw a limit to thought, we should have to find both sides of the limit thinkable (i.e. we should have to be able to think what cannot be thought). It will therefore only be in language that the limit can be drawn, and what lies on the other side of the limit will simply be nonsense.”[6]

Thus, through the philosophical study of language, we can identify the boundaries of philosophical inquiry.